New Research

Translating Research into Practice and Policy...

New research from HIP investigators in the Journal of Clinical Oncology finds that adjuvant chemotherapy did not substantially improve overall survival among Medicare patients with stage II colon cancer, even when their cancer had poor prognostic features. (PubMed Link)

O'Connor ES, Greenblatt DY, LoConte N, Gangnon R, Liou J, Heise CP, Smith M. "Adjuvant chemotherapy for stage II colon cancer with poor prognostic features." J Clin Oncol 2011;29(25):3381-8.

"Given consistency with clinical trial data and the lack of compelling data to the contrary, this report must be viewed as more than merely hypothesis-generating, and should discourage routine use of adjuvant treatment in this patient population." -- Editorial by Neal J. Meropol, MD, Associate Director for Clinical Research at the Case Comprehensive Cancer Center (PubMed Link)



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